Search results for "observational [Methods]"
showing 10 items of 897 documents
Effectiveness and safety of dexamphetamine sulfate (Attentin
2021
Abstract Background: Randomized controlled trials have shown that dexamphetamine sulfate (DEX) is efficacious in the treatment of attention-deficit/hyperactivity disorder (ADHD) in children and adolescents; however, data on the effectiveness and safety of DEX in routine practice are scarce. Objective: This study investigated the long-term effectiveness and safety of Attentin® (immediate-release DEX) in children and adolescents with ADHD in routine practice. Methods: ATTENTION was a multicenter, prospective, observational, non-interventional study that enrolled pediatric patients with ADHD (aged 6-17 years) with a clinically inadequate response to previous methylphenidate (MPH) treatment. Pa…
mRNA COVID-19 vaccines do not increase the short-term risk of clinical relapses in multiple sclerosis
2021
Multiple sclerosis (MS) is a chronic, immune-mediated disorder of the central nervous system. A novel coronavirus, namely SARS-CoV-2, has been recently responsible for the highly infectious disease referred as COVID-19, rapidly spreading all over the world. Many vaccines have been developed to control COVID-19 pandemic, including the mRNA vaccines Pfizer/BioNTech (BNT162b2) and Moderna (mRNA1273).1 The vaccination of people with MS (pwMS) has been recommended by several national and international MS societies. However, effectiveness and safety of anti-COVID-19 mRNA vaccines in MS need to be confirmed. The aim of this study was to evaluate the short-term risk of clinical relapses in pwMS in …
Chronic Spontaneous Urticaria and Type 1 Diabetes Mellitus—Does Quality of Life Impairment Always Reflect Health Danger?
2020
Background and aims: Chronic spontaneous urticaria (CSU) and diabetes mellitus type 1 (T1DM) may compromise the quality of life (QoL). We decided to compare the QoL of T1DM patients to those suffering from CSU. Materials and methods: Sixty-six patients with well-controlled T1DM (male 52%) in the mean age of (SD) 36.3 (11.09) years and 51 patients with CSU (male 33%) in the mean age of (SD) 35.8 (8.53) years were enrolled in this observational study. All the participants completed a Short-Form 36 (SF-36) QoL. Results: The QoL related to social functioning was significantly worse among CSU patients. There were differences related to gender found in the group of patients with T1DM&mdash
Paediatric acute rheumatic fever in developed countries: Neglected or negligible disease? Results from an observational study in Lombardy (Italy)
2018
Introduction: Acute Rheumatic Fever (ARF) is a multisystemic disease that results from an autoimmune reaction due to group A streptococcal infection. The disease affects predominantly children aged 5 to 15 years and although its incidence in developed Countries declined since the early 1900s, to date there is a paucity of data that confirm this epidemiological trend. Objective: The study aimed to assess the burden of ARF in term of hospitalization and to describe the characteristics of acute rheumatic fever (ARF) in the paediatric population of Lombardy. Study design: The study was carried out by analyzing hospital discharge records of patients resident of Lombardy and aged 0–17 years old w…
Observational study on safety and tolerability of duloxetine in the treatment of female stress urinary incontinence in German routine practice
2013
Aims To evaluate the safety and tolerability of duloxetine during routine clinical care in women with stress urinary incontinence (SUI) in Germany, and in particular, to identify previously unrecognized safety issues as uncommon adverse reactions, and the influence of confounding factors present in clinical practice on the safety profile of duloxetine.
Evaluación de un programa de conciliación e información al paciente trasplantado cardíaco
2010
Introduction: The objective is to assess a pharmaceutical care programme for heart transplant patients upon patient admission and discharge. Material y methods: Observational study of heart transplant patients, performed during the first quarter of 2007. Upon admission, the patient was interviewed regarding home treatments, adherence, allergies and adverse effects, and his/her prescriptions were compared with the last discharge report (drug reconciliation). At time of discharge, treatment was checked against the last hospital prescription (reconciliation) and an informative report was drawn up and personally delivered to the patient. Subsequently, a satisfaction questionnaire was carried ou…
Impulsivity and physical activity: A T-Pattern detection of motor behavior profiles.
2020
The relation between impulsivity and physical activity has been scantly investigated. Actually, during physical activity, several goals are achieved on the basis of a certain dose of impulsiveness. This study detects motor and interactive behavior profiles from athletes with traits of impulsiveness, moderate impulsiveness and non-impulsiveness, performing open motor tasks concerning material, space and interaction behaviors. A specific test was administered to assess the impulsivity profiles of athletes; then the Observational System of Motor Skills, Space, Time and Interaction (OSMOSTI), was used to observe and detect movement sequences patterns throughout T-Pattern detection and analysis …
Observational Cosmology at High Redshift
2007
Summary. I offer a brief review of the evolution and present status of our observational knowledge of the high-redshift Universe. In particular, I focus on the different methods that have been devised to select distant objects, and the observational evidence in hand to support (or else) the standard evolutionary scenario. 1 How High is High? The study of objects at cosmological distances from us started in the 1960s with the discovery and identification of quasi-stellar radiosources. The explanation of the features observed in the optical spectra of these objects as highly redshifted hydrogen lines opened the door to the very distant Universe. For the next 30 years after the discovery of qu…
Meßfehlerschätzung bei der MR-tomographischen Volumetrie des linken Ventrikels mit Mehrschicht-Technik
1992
A multi-slice technique for MRT measurements of the left ventricular volume is much faster than the use of single-slice methods and is therefore better tolerated, leaving time for additional measurements. The end-diastolic left ventricular volume can be reliably measured by this method (123.3 +/- 13.5 ml vs. 124.1 +/- ml). The end-systolic volume is consistently overestimated by 23.7 +/- 18.3% compared with the reference value obtained by single slice measurements (47.9 +/- 8.9 ml vs 39.1 +/- 7.9 ml). Correspondingly, stroke volume and ejection fraction is underestimated on average by 10.6 +/- 9.7% and 10.6 +/- 7.6% respectively).
Very peculiar wind from BD+53°2790, the optical counterpart to 4U 2206+54
2008
BD+53 2790, an O9.5Vp star, is the optical counterpart to the HMXRB 4U 2206+54. This system was classified initially as a BeX, but observational evidence soon stressed the need to revise this classification. The permanent asymmetry in the H-alpha line profiles (in contrast with the cyclic variations shown by Be stars), the variations in the profile of this line in time scales of hours (while time scales from weeks to months are expected in Be stars), and the lack of correlation between IR observables and H-alpha line parameters, strongly suggest that, while BD+53 2790 contains a circunstellar disc, it is not like the one present in Be stars. Furthermore, there is evidence of overabundance o…